Researchers at Melbourne’s Baker Heart and Diabetes Institute have discovered a method that could eliminate the need for regular insulin injections.
The team led by Professor Sam El-Osta identified two drugs, previously approved by the U.S. Food and Drug Administration for rare cancers, that are capable of rapidly restoring insulin production in cells damaged by diabetes.
For type 1 diabetes, which represents about 10 percent of all diabetes cases in Australia, the immune system destroys pancreatic cells, necessitating daily insulin injections to manage the disease.
When stimulated by small molecule inhibitors in the drugs, the cells were found to respond to glucose and produce insulin within 48 hours....
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