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The Complicated Nature of HRT in Menopause Requires Cautious Approach

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Advice about whether women undergoing menopause should take hormone replacement therapy (HRT) has oscillated between two extremes in the past couple decades. At first, doctors rubber-stamped HRT for the vast number of women with symptoms such as hot flashes, night sweats, sleep apnea, vaginal atrophy, and cognitive decline. Then a slight uptick in the risk of breast cancer among one of two cohorts in) a 2002 study by the Women’s Health Initiative (WHI) halted HRT recommendations. Media headlines stirred up panic among women and doctors who believed there were more harms than benefits to HRT—a message that is beginning to flip. As a clearer picture emerges, doctors are better able to identify who should get HRT and who should not....

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